Cailynn Johnson

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2025-06-25 03:13:54 -

Monoclonal antibody glycosylation
Monoclonal antibody glycosylation is a critical quality attribute that directly affects therapeutic efficacy, safety, and regulatory compliance. Glycans—particularly N-linked glycans at Asn 297 of the Fc region—govern key functions such as antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), serum half-life, and immunogenicity. Creative...

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2025-06-25 03:13:08 -

Exploring Glycoproteins in Cancer Research: Potential for Diagnosis and Therapeutics
Glycobiology, the study of carbohydrates and their interactions in biological systems, has gained considerable attention from researchers and scientists in recent years. This is largely due to the recognition of glycans—complex carbohydrates—as critical components in various biological processes, including cell signaling, immunity, and disease progression. Among the important areas...

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2025-06-25 03:12:45 -

Advancing Liposome Drug Delivery: New Hope for Cancer Patients
A novel liposome product, doxorubicin hydrocholoride liposomal injection, has received FDA approval as well as European Commission authorization to be used in the treatment of a variety of cancers, including ovarian cancer, acquired immune deficiency syndrome (AIDS)-related Kaposi's sarcoma, and multiple myeloma. It is no doubt another piece of good news for...

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2025-06-25 03:12:19 -

Development Journey of Liposome Drug Delivery
According to the latest market report about liposome and nanoparticle drug delivery, the market size and market share continue to expand in 2023 and will be expected to touch USD 8977.8 million by 2028. These data obviously prove the extensive promise of broad applications of liposome drug delivery in a variety of disease treatments. For many years, liposomes as potential drug carriers...

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2025-06-25 03:11:55 -

Targeting Cadmium: The Role of Hapten Design in Antibody Engineering
From Molecule to Antibody: The Impact of Hapten Synthesis on Cadmium Research The field of antibody development has witnessed significant advancements, particularly with the emergence of novel strategies in hapten design. Haptens, small molecules that can elicit an immune response, play a pivotal role in generating antibodies with high specificity and affinity. This article explores the impact...

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2025-06-25 03:11:27 -

Unlocking Potential: Advancements in Small-Molecule Antibody Therapy and Diagnostics
Antibodies, the extraordinary proteins that serve as the frontline troops of the human immune system, have recently gained attention for their ability to combat tiny compounds known as haptens. Because of their small size, these elusive targets present particular difficulty for the immune system to identify as foreign invaders. However, researchers' inventiveness has resulted in the creation of...

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2025-06-25 03:11:00 -

Monkeypox Uncovered: The Latest Updates in Science and Innovations
Monkeypox, a zoonotic viral infection, has recently garnered significant attention due to its rapid spread and the declaration of a global health emergency by the World Health Organization (WHO). As a biotech researcher, it is crucial to stay abreast of the latest developments in the field to understand the virus better and develop effective diagnostic and therapeutic strategies. Understanding...

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2025-06-25 03:10:36 -

Monkeypox Vaccine for Children
The World Health Organization (WHO) has recently taken a significant step by authorizing the first monkeypox vaccine for children. This development is crucial in the ongoing battle against the virus, particularly as it continues to spread in various regions, including parts of Africa. This authorization is aimed at protecting children, one of the most vulnerable groups, from the debilitating...

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2025-05-26 05:51:57 -

Applications of Macrophages in Disease Treatment Research
Macrophages, integral components of the immune system, play a crucial role in maintaining homeostasis and combating infections. In recent years, researchers have uncovered the diverse applications of macrophages in disease treatment research. Atherosclerosis, a leading cause of cardiovascular diseases, involves the accumulation of plaques within arterial walls. Macrophages contribute...

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2025-05-26 05:51:17 -

Emerging Research on CAR-Modified Macrophages: A Breakthrough in Liver Cancer Treatment
Liver cancer, specifically hepatocellular carcinoma (HCC), is one of the leading causes of cancer-related deaths worldwide. The tumor microenvironment, which includes various immune cells, plays a significant role in cancer progression and response to therapy. Among these immune cells, macrophages have been identified as key players due to their diverse functions and plasticity. The Role of...

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2025-05-26 05:50:43 -

The Path to Accurate Glycan Analysis: Techniques and Technologies in Glycan Research
Glycans, also known as carbohydrates or polysaccharides, are fundamental constituents of all cellular life. They play essential roles in various biological processes, including cell-to-cell communication, immune response, and disease progression, among others. Accurate glycan purification, glycan identification, and anti-glycan antibody assays are crucial in advancing our understanding of...

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2025-05-26 05:50:06 -

Unveiling the Role of Anti-Glycan Antibodies in Disease Diagnosis and Treatment
In the intricate realm of medical diagnostics and therapeutic advancements, antibodies targeting glycans have emerged as pivotal players. Glycans, complex sugar molecules decorating proteins and lipids, play crucial roles in cellular communication, immune responses, and disease pathogenesis. Harnessing antibodies specific to these glycans opens new avenues for diagnosis, treatment, and...

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